Harrison's Manual of Medicine
SYSTEMIC SCLEROSIS (SCLERODERMA, SSc)
DEFINITION AND PATHOGENESIS
SSc is a multisystem disorder characterized by thickening of the skin (scleroderma) and distinctive involvement of multiple internal organs (chiefly GI tract, lungs, heart, and kidney). Pathogenesis unclear; involves immunologic mechanisms leading to vascular endothelial damage and activation of fibroblasts.
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Citation
Kasper, Dennis L., et al., editors. "SYSTEMIC SCLEROSIS (SCLERODERMA, SSc)." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623392/all/SYSTEMIC_SCLEROSIS__SCLERODERMA__SSc_.
SYSTEMIC SCLEROSIS (SCLERODERMA, SSc). In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623392/all/SYSTEMIC_SCLEROSIS__SCLERODERMA__SSc_. Accessed December 11, 2024.
SYSTEMIC SCLEROSIS (SCLERODERMA, SSc). (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623392/all/SYSTEMIC_SCLEROSIS__SCLERODERMA__SSc_
SYSTEMIC SCLEROSIS (SCLERODERMA, SSc) [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2024 December 11]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623392/all/SYSTEMIC_SCLEROSIS__SCLERODERMA__SSc_.
* Article titles in AMA citation format should be in sentence-case
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T1 - SYSTEMIC SCLEROSIS (SCLERODERMA, SSc)
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ED - Jameson,J Larry,
ED - Loscalzo,Joseph,
ED - Kasper,Dennis L,
ED - Fauci,Anthony S,
ED - Hauser,Stephen L,
ED - Longo,Dan L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623392/all/SYSTEMIC_SCLEROSIS__SCLERODERMA__SSc_
PB - McGraw Hill Inc.
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DB - Harrison's Manual of Medicine
DP - Unbound Medicine
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