LIVER TRANSPLANTATION
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Consider in the absence of contraindications for chronic, irreversible, progressive liver disease or fulminant hepatic failure when no alternative therapy is available (Table 157-4).
CHILDREN | ADULTS |
---|---|
Biliary atresia | Primary biliary cirrhosis |
Neonatal hepatitis | Secondary biliary cirrhosis |
Congenital hepatic fibrosis | Primary sclerosing cholangitis |
Alagille’s syndromea | Autoimmune hepatitis |
Byler’s diseaseb | Caroli’s diseasec |
α1-Antitrypsin deficiency | Cryptogenic cirrhosis |
Inherited disorders of metabolism | Chronic hepatitis with cirrhosis |
Wilson’s disease | Hepatic vein thrombosis |
Tyrosinemia | Fulminant hepatitis |
Glycogen storage diseases | Alcoholic cirrhosis |
Lysosomal storage diseases | Chronic viral hepatitis |
Protoporphyria | Primary hepatocellular malignancies |
Crigler-Najjar disease type I | Hepatic adenomas |
Familial hypercholesterolemia | Nonalcoholic steatohepatitis |
Primary hyperoxaluria type I | Familial amyloid polyneuropathy |
Hemophilia |
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Consider in the absence of contraindications for chronic, irreversible, progressive liver disease or fulminant hepatic failure when no alternative therapy is available (Table 157-4).
CHILDREN | ADULTS |
---|---|
Biliary atresia | Primary biliary cirrhosis |
Neonatal hepatitis | Secondary biliary cirrhosis |
Congenital hepatic fibrosis | Primary sclerosing cholangitis |
Alagille’s syndromea | Autoimmune hepatitis |
Byler’s diseaseb | Caroli’s diseasec |
α1-Antitrypsin deficiency | Cryptogenic cirrhosis |
Inherited disorders of metabolism | Chronic hepatitis with cirrhosis |
Wilson’s disease | Hepatic vein thrombosis |
Tyrosinemia | Fulminant hepatitis |
Glycogen storage diseases | Alcoholic cirrhosis |
Lysosomal storage diseases | Chronic viral hepatitis |
Protoporphyria | Primary hepatocellular malignancies |
Crigler-Najjar disease type I | Hepatic adenomas |
Familial hypercholesterolemia | Nonalcoholic steatohepatitis |
Primary hyperoxaluria type I | Familial amyloid polyneuropathy |
Hemophilia |
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