EBOLA AND MARBURG VIRUS INFECTIONS is a topic covered in the Harrison's Manual of Medicine.

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The family Filoviridae contains two genera, Marburgvirus and Ebolavirus, that consist of negative-sense, single-stranded RNA viruses capable of infecting humans. Ebolavirus has five species named for their original site of recognition, and Marburgvirus has two species.

  • Both Marburg virus and Ebola virus are biosafety level 4 pathogens because of high mortality rates (except for Reston virus, an Ebola virus, which is nonpathogenic for humans) and aerosol infectivity.

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