EBOLA AND MARBURG VIRUS INFECTIONS

MICROBIOLOGY

The family Filoviridae contains two genera, Marburgvirus and Ebolavirus, that consist of negative-sense, single-strand RNA viruses capable of infecting humans. Ebolavirus has five species named for their original sites of recognition, and Marburgvirus has two species.

Both Marburg virus and Ebola virus are biosafety level 4 pathogens because of high mortality rates (except for Reston virus, an Ebola virus, which is nonpathogenic for humans) and aerosol infectivity.

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