Harrison's Manual of Medicine
Chapter 159: Diseases of Immediate-Type Hypersensitivity
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DEFINITION
These diseases result from IgE-dependent release of mediators from sensitized basophils and mast cells upon contact with an offending antigen (allergen). Associated disorders include anaphylaxis (Chap. 28: Anaphylaxis), allergic rhinitis, urticaria, asthma, and eczematous (atopic) dermatitis.
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DEFINITION
These diseases result from IgE-dependent release of mediators from sensitized basophils and mast cells upon contact with an offending antigen (allergen). Associated disorders include anaphylaxis (Chap. 28: Anaphylaxis), allergic rhinitis, urticaria, asthma, and eczematous (atopic) dermatitis.
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