Harrison's Manual of Medicine
NORMAL GASTROINTESTINAL FUNCTION
To view the entire topic, please sign in or purchase a subscription.
Harrison’s Manual of Medicine 20th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:
-- The first section of this topic is shown below --
ABSORPTION OF FLUID AND ELECTROLYTES
Fluid delivery to the GI tract is 8–10 L/d, including 2 L/d ingested; most is absorbed in small bowel. About 2 L/d is delivered to the colon; about 0.2 L/d is excreted in the stool. Colonic absorption is normally 0.05–2 L/d, with capacity for 6 L/d if required. Intestinal water absorption passively follows active transport of Na+, Cl–, glucose, and bile salts. Additional transport mechanisms include Cl–/HCO3– exchange, Na+/H+ exchange, H+, K+, Cl–, and HCO3– secretion, Na+-glucose cotransport, and active Na+ transport across the basolateral membrane by Na+,K+-ATPase.
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
ABSORPTION OF FLUID AND ELECTROLYTES
Fluid delivery to the GI tract is 8–10 L/d, including 2 L/d ingested; most is absorbed in small bowel. About 2 L/d is delivered to the colon; about 0.2 L/d is excreted in the stool. Colonic absorption is normally 0.05–2 L/d, with capacity for 6 L/d if required. Intestinal water absorption passively follows active transport of Na+, Cl–, glucose, and bile salts. Additional transport mechanisms include Cl–/HCO3– exchange, Na+/H+ exchange, H+, K+, Cl–, and HCO3– secretion, Na+-glucose cotransport, and active Na+ transport across the basolateral membrane by Na+,K+-ATPase.
There's more to see -- the rest of this entry is available only to subscribers.
