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GRAM-NEGATIVE ENTERIC BACTERIA

GRAM-NEGATIVE ENTERIC BACTERIA is a topic covered in the Harrison's Manual of Medicine.

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GENERAL CONSIDERATIONS

Gram-negative bacilli (GNB) are normal components of the human colonic flora and/or a number of environmental habitats and can colonize mucosal and skin surfaces, especially in pts in long-term care facilities and hospital settings. GNB cause a wide variety of infections involving diverse anatomic sites in both healthy and compromised hosts; extraintestinal infections due to Escherichia coli and, to a lesser degree, Klebsiella species are most common. Isolation of GNB from any sterile site almost always implies infection, whereas isolation from nonsterile sites requires clinical correlation. Early appropriate antimicrobial therapy improves outcomes. Given worldwide increases in multidrug-resistant GNB (e.g., due to extended-spectrum β-lactamases [ESBLs] and AmpC β-lactamases), combination empirical antimicrobial therapy pending susceptibility results may be appropriate for critically ill pts.

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Citation

Loscalzo, Joseph, et al., editors. "GRAM-NEGATIVE ENTERIC BACTERIA." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA.
GRAM-NEGATIVE ENTERIC BACTERIA. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA. Accessed April 18, 2019.
GRAM-NEGATIVE ENTERIC BACTERIA. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA
GRAM-NEGATIVE ENTERIC BACTERIA [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 18]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - GRAM-NEGATIVE ENTERIC BACTERIA ID - 623660 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -