GRAM-NEGATIVE ENTERIC BACTERIA

GRAM-NEGATIVE ENTERIC BACTERIA is a topic covered in the Harrison's Manual of Medicine.

To view the entire topic, please or purchase a subscription.

Harrison’s Manual of Medicine 19th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:

Harrison’s Manual of Medicine - App + Web

-- The first section of this topic is shown below --

GENERAL CONSIDERATIONS

Gram-negative bacilli (GNB) are normal components of the human colonic flora and/or a number of environmental habitats and can colonize mucosal and skin surfaces, especially in pts in long-term care facilities and hospital settings. GNB cause a wide variety of infections involving diverse anatomic sites in both healthy and compromised hosts; extraintestinal infections due to Escherichia coli and, to a lesser degree, Klebsiella species are most common. Isolation of GNB from any sterile site almost always implies infection, whereas isolation from nonsterile sites requires clinical correlation. Early appropriate antimicrobial therapy improves outcomes. Given worldwide increases in multidrug-resistant GNB (e.g., due to extended-spectrum β-lactamases [ESBLs] and AmpC β-lactamases), combination empirical antimicrobial therapy pending susceptibility results may be appropriate for critically ill pts.

-- To view the remaining sections of this topic, please or purchase a subscription --

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - GRAM-NEGATIVE ENTERIC BACTERIA ID - 623660 Y1 - 2017 PB - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623660/all/GRAM_NEGATIVE_ENTERIC_BACTERIA ER -