Harrison's Manual of Medicine
MYELOPROLIFERATIVE SYNDROMES
The three major myeloproliferative syndromes are polycythemia vera, idiopathic myelofibrosis, and essential thrombocytosis. All are clonal disorders of hematopoietic stem cells and all are associated with a mutation in the JAK2 kinase (V617F) that results in activation of the kinase. The mutation is seen in 90% of pts with polycythemia vera and ∼45% of pts with idiopathic myelofibrosis and essential thrombocytosis.
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Citation
Kasper, Dennis L., et al., editors. "MYELOPROLIFERATIVE SYNDROMES." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623595/all/MYELOPROLIFERATIVE_SYNDROMES.
MYELOPROLIFERATIVE SYNDROMES. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623595/all/MYELOPROLIFERATIVE_SYNDROMES. Accessed December 21, 2024.
MYELOPROLIFERATIVE SYNDROMES. (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623595/all/MYELOPROLIFERATIVE_SYNDROMES
MYELOPROLIFERATIVE SYNDROMES [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2024 December 21]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623595/all/MYELOPROLIFERATIVE_SYNDROMES.
* Article titles in AMA citation format should be in sentence-case
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T1 - MYELOPROLIFERATIVE SYNDROMES
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ED - Kasper,Dennis L,
ED - Fauci,Anthony S,
ED - Hauser,Stephen L,
ED - Longo,Dan L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623595/all/MYELOPROLIFERATIVE_SYNDROMES
PB - McGraw Hill Inc.
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DB - Harrison's Manual of Medicine
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