LEUKOCYTOSIS

LEUKOCYTOSIS is a topic covered in the Harrison's Manual of Medicine.

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Approach to the patient: Leukocytosis

Review smear (are abnormal cells present?) and obtain differential count. The normal values for concentration of blood leukocytes are shown in Table 64-1.

TABLE 64-1: Normal Values for Leukocyte Concentration in Blood
CELL TYPEMEAN, CELLS/μL95% CONFIDENCE INTERVALS, CELLS/μLTOTAL WBC, %
Neutrophil36501830–725030–60
Lymphocyte25001500–400020–50
Monocyte430200–9502–10
Eosinophil1500–7000.3–5
Basophil300–1500.6–1.8

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Approach to the patient: Leukocytosis

Review smear (are abnormal cells present?) and obtain differential count. The normal values for concentration of blood leukocytes are shown in Table 64-1.

TABLE 64-1: Normal Values for Leukocyte Concentration in Blood
CELL TYPEMEAN, CELLS/μL95% CONFIDENCE INTERVALS, CELLS/μLTOTAL WBC, %
Neutrophil36501830–725030–60
Lymphocyte25001500–400020–50
Monocyte430200–9502–10
Eosinophil1500–7000.3–5
Basophil300–1500.6–1.8

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