ACNE is a topic covered in the Harrison's Manual of Medicine.

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Harrison’s Manual of Medicine

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Usually a self-limited disorder of teenagers and young adults. Comedones (small cysts formed in hair follicles) are clinical hallmark; often accompanied by inflammatory lesions of papules, pustules, or nodules; may scar in severe cases.

Treatment: Acne Vulgaris

Careful cleaning and removal of oils; oral tetracycline or erythromycin; topical antibacterials (e.g., benzoyl peroxide), topical retinoic acid. Systemic isotretinoin only for unresponsive severe nodulocystic acne (risk of severe adverse events including teratogenicity and possible association with depression).

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