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VENOMOUS SNAKEBITES is a topic covered in the Harrison's Manual of Medicine.

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  • Epidemiology: Worldwide, 1.2–5.5 million snakebites are sustained each year, with 421,000–1,841,000 envenomations and 20,000–94,000 deaths.
    • Bite rates are highest in temperate and tropical climates where populations subsist by manual agriculture and fishing.
    • Differentiation of venomous from nonvenomous snake species can be difficult; color pattern is notoriously misleading.
  • Clinical features: Snake venoms are complex mixtures of enzymes and other substances that promote vascular leaking, cause tissue necrosis, affect the coagulation cascade, and impair organ function.
    • Specific presentations differ somewhat with the particular snake species.
    • Systemic symptoms may include hypotension, pulmonary edema, hemorrhage, altered mental status, or paralysis (including muscles of respiration).
  • Prognosis: The overall mortality rate for venomous snakebite is <1% among U.S. victims who receive antivenom; the incidence of permanent functional loss in a bitten extremity is substantial.

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Loscalzo, Joseph, et al., editors. "VENOMOUS SNAKEBITES." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623528/all/VENOMOUS_SNAKEBITES.
VENOMOUS SNAKEBITES. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623528/all/VENOMOUS_SNAKEBITES. Accessed April 23, 2019.
VENOMOUS SNAKEBITES. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623528/all/VENOMOUS_SNAKEBITES
VENOMOUS SNAKEBITES [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 23]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623528/all/VENOMOUS_SNAKEBITES.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - VENOMOUS SNAKEBITES ID - 623528 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623528/all/VENOMOUS_SNAKEBITES PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -