THYROTOXICOSIS is a topic covered in the Harrison's Manual of Medicine.

To view the entire topic, please or purchase a subscription.

Harrison’s Manual of Medicine 19th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:

Harrison’s Manual of Medicine - App + Web

-- The first section of this topic is shown below --


Causes of thyroid hormone excess include primary hyperthyroidism (Graves’ disease, toxic multinodular goiter [MNG], toxic adenoma, iodine excess); thyroid destruction (subacute thyroiditis, silent thyroiditis, amiodarone, radiation); extrathyroidal sources of thyroid hormone (thyrotoxicosis factitia, struma ovarii, functioning follicular carcinoma); and secondary hyperthyroidism (TSH-secreting pituitary adenoma, thyroid hormone resistance syndrome, human chorionic gonadotropin [hCG]-secreting tumors, gestational thyrotoxicosis). Graves’ disease, caused by activating TSH-receptor antibodies, is the most common cause of thyrotoxicosis and accounts for 60–80% of cases. Its prevalence in women is 10-fold higher than in men; its peak occurrence is at age 20–50 years.

-- To view the remaining sections of this topic, please or purchase a subscription --


* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - THYROTOXICOSIS ID - 623417 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -