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SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH) is a topic covered in the Harrison's Manual of Medicine.

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Excessive or inappropriate production of AVP predisposes to hyponatremia, reflecting water retention. The evaluation of hyponatremia is described in Chap. 1. Etiologies of SIADH include neoplasms, lung infections, CNS disorders, and drugs (Table 169-1).

 Carcinomas Guillain-Barré syndrome
  Lung Multiple sclerosis
  Duodenum Delirium tremens
  Pancreas Amyotrophic lateral sclerosis
  Ovary Hydrocephalus
  Bladder, ureter Psychosis
 Other neoplasms Peripheral neuropathy
  ThymomaCongenital malformations
  Mesothelioma Agenesis corpus callosum
  Bronchial adenoma Cleft lip/palate
  Carcinoid Other midline defects
  Ewing’s sarcoma Acute intermittent porphyria
Head traumaPulmonary
Infections Asthma
 Pneumonia, bacterial or viral Pneumothorax
 Abscess, lung or brain Positive-pressure respiration
 Cavitation (aspergillosis)Drugs
 Tuberculosis, lung or brain Vasopressin or desmopressin
 Meningitis, bacterial or viral Chlorpropamide
 Encephalitis Oxytocin, high dose
 AIDS Vincristine
Vascular Carbamazepine

 Cerebrovascular occlusions, hemorrhage


 Cavernous sinus thrombosis




 X-linked recessive

 Tricyclic antidepressants

 (V2 receptor gene)

 Monoamine oxidase inhibitors
 Serotonin reuptake inhibitors

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Loscalzo, Joseph, et al., editors. "SYNDROME of INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH)." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623415/all/SYNDROME_OF_INAPPROPRIATE_ANTIDIURETIC_HORMONE__SIADH_.
SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH). In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623415/all/SYNDROME_OF_INAPPROPRIATE_ANTIDIURETIC_HORMONE__SIADH_. Accessed April 18, 2019.
SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH). (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623415/all/SYNDROME_OF_INAPPROPRIATE_ANTIDIURETIC_HORMONE__SIADH_
SYNDROME of INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH) [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 18]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623415/all/SYNDROME_OF_INAPPROPRIATE_ANTIDIURETIC_HORMONE__SIADH_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE (SIADH) ID - 623415 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623415/all/SYNDROME_OF_INAPPROPRIATE_ANTIDIURETIC_HORMONE__SIADH_ PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -