Harrison's Manual of Medicine
SYSTEMIC MASTOCYTOSIS
To view the entire topic, please log in or purchase a subscription.
Harrison’s Manual of Medicine 20th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:
-- The first section of this topic is shown below --
DEFINITION
A systemic disorder defined by a clonal expansion of mast cells that in most instances is indolent and nonmalignant. Generally involves bone marrow, skin, gastrointestinal (GI) mucosa, liver, and spleen. Classified as cutaneous mastocytosis with variants, five systemic forms (indolent, smoldering, associated with concomitant hematologic non–mast cell lineage disease, aggressive, mast cell leukemia), and rare mast cell sarcoma.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
DEFINITION
A systemic disorder defined by a clonal expansion of mast cells that in most instances is indolent and nonmalignant. Generally involves bone marrow, skin, gastrointestinal (GI) mucosa, liver, and spleen. Classified as cutaneous mastocytosis with variants, five systemic forms (indolent, smoldering, associated with concomitant hematologic non–mast cell lineage disease, aggressive, mast cell leukemia), and rare mast cell sarcoma.
There's more to see -- the rest of this entry is available only to subscribers.
