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    SYSTEMIC MASTOCYTOSIS

    SYSTEMIC MASTOCYTOSIS is a topic covered in the Harrison's Manual of Medicine.

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    DEFINITION

    A systemic disorder defined by a clonal expansion of mast cells that in most instances is indolent and nonmalignant. Generally involves bone marrow, skin, gastrointestinal (GI) mucosa, liver, and spleen. Classified as cutaneous mastocytosis with variants and four systemic forms: indolent, associated with concomitant hematologic disorder, aggressive, and mast cell leukemia. Mast cell sarcoma and extracutaneous mastocytomas are rare solid mast cell tumors.

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    Citation

    * When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - SYSTEMIC MASTOCYTOSIS ID - 623389 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623389/all/SYSTEMIC_MASTOCYTOSIS PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -