Harrison's Manual of Medicine
URTICARIA AND ANGIOEDEMA
DEFINITION
May occur together or separately. Urticaria involves only the superficial dermis and presents as pruritic, circumscribed wheals with raised serpiginous borders and blanched centers. Angioedema involves deeper layers of skin and may include subcutaneous tissue; it is marked by dramatic swelling with more pain than pruritus. Recurrent episodes of urticaria and/or angioedema of <6 weeks duration are considered acute, whereas attacks persisting beyond this period are chronic.
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Citation
Kasper, Dennis L., et al., editors. "URTICARIA and ANGIOEDEMA." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623387/all/URTICARIA_AND_ANGIOEDEMA.
URTICARIA AND ANGIOEDEMA. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623387/all/URTICARIA_AND_ANGIOEDEMA. Accessed February 22, 2025.
URTICARIA AND ANGIOEDEMA. (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623387/all/URTICARIA_AND_ANGIOEDEMA
URTICARIA and ANGIOEDEMA [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2025 February 22]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623387/all/URTICARIA_AND_ANGIOEDEMA.
* Article titles in AMA citation format should be in sentence-case
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