TOXIC AND DRUG-INDUCED HEPATITIS

DOSE-DEPENDENT (DIRECT HEPATOTOXINS)

Onset is within 48 h, predictable, necrosis around terminal hepatic venule—e.g., carbon tetrachloride, benzene derivatives, mushroom poisoning, acetaminophen, or microvesicular steatosis (e.g., tetracyclines, valproic acid).

There's more to see -- the rest of this topic is available only to subscribers.