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PEPTIC ULCER DISEASE

PEPTIC ULCER DISEASE is a topic covered in the Harrison's Manual of Medicine.

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Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. PUD results when “aggressive” factors (gastric acid, pepsin) overwhelm “defensive” factors involved in mucosal resistance (gastric mucus, bicarbonate, microcirculation, prostaglandins, mucosal “barrier”) and from effects of Helicobacter pylori.

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Citation

Fauci, Anthony S., et al., editors. "PEPTIC ULCER DISEASE." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. Harrison's Manual of Medicine, harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE.

PEPTIC ULCER DISEASE. In: Fauci AS, Hauser SL, Jameson JL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE. Accessed February 17, 2019.

PEPTIC ULCER DISEASE. (2017). In Fauci, A. S., Hauser, S. L., Jameson, J. L., Kasper, D. L., Longo, D. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE

PEPTIC ULCER DISEASE [Internet]. In: Fauci AS, Hauser SL, Jameson JL, Kasper DL, Longo DL, Loscalzo J, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 February 17]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - PEPTIC ULCER DISEASE ID - 623364 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -