PEPTIC ULCER DISEASE is a topic covered in the
Harrison's Manual of Medicine.
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Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. PUD results when “aggressive” factors (gastric acid, pepsin) overwhelm “defensive” factors involved in mucosal resistance (gastric mucus, bicarbonate, microcirculation, prostaglandins, mucosal “barrier”) and from effects of Helicobacter pylori.
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Citation
Loscalzo, Joseph, et al., editors. "PEPTIC ULCER DISEASE." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE.
PEPTIC ULCER DISEASE. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE. Accessed December 6, 2019.
PEPTIC ULCER DISEASE. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE
PEPTIC ULCER DISEASE [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 December 06]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE.
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T1 - PEPTIC ULCER DISEASE
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ED - Loscalzo,Joseph,
ED - Jameson,J Larry,
ED - Longo,Dan L,
ED - Hauser,Stephen L,
ED - Fauci,Anthony S,
ED - Kasper,Dennis L,
BT - Harrison's Manual of Medicine
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PB - McGraw Hill Inc.
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DB - Harrison's Manual of Medicine
DP - Unbound Medicine
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Harrison's Manual of Medicine
