PEPTIC ULCER DISEASE is a topic covered in the
Harrison's Manual of Medicine.
To view the entire topic, please sign in or purchase a subscription.
Harrison’s Manual of Medicine 20th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:

-- The first section of this topic is shown below --
Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. PUD results when “aggressive” factors (gastric acid, pepsin) overwhelm “defensive” factors involved in mucosal resistance (gastric mucus, bicarbonate, microcirculation, prostaglandins, mucosal “barrier”) and from effects of Helicobacter pylori.
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
Citation
Loscalzo, Joseph, et al., editors. "PEPTIC ULCER DISEASE." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE.
PEPTIC ULCER DISEASE. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE. Accessed December 6, 2019.
PEPTIC ULCER DISEASE. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE
PEPTIC ULCER DISEASE [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 December 06]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE.
TY - ELEC
T1 - PEPTIC ULCER DISEASE
ID - 623364
ED - Loscalzo,Joseph,
ED - Jameson,J Larry,
ED - Longo,Dan L,
ED - Hauser,Stephen L,
ED - Fauci,Anthony S,
ED - Kasper,Dennis L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623364/all/PEPTIC_ULCER_DISEASE
PB - McGraw Hill Inc.
ET - 19
DB - Harrison's Manual of Medicine
DP - Unbound Medicine
ER -