COR PULMONALE is a topic covered in the Harrison's Manual of Medicine.

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RV enlargement and/or altered function resulting from primary lung disease; leads to RV hypertrophy and eventually to RV failure. Etiologies include:

  • Pulmonary parenchymal or airway disease leading to hypoxemic vasoconstriction: e.g., chronic obstructive pulmonary disease (COPD), interstitial lung diseases, bronchiectasis, cystic fibrosis (Chaps. 131 and 134).
  • Diseases of the pulmonary vasculature: e.g., recurrent pulmonary emboli, pulmonary arterial hypertension (PAH) (Chap. 127), vasculitis, sickle cell anemia.
  • Inadequate mechanical ventilation (chronic hypoventilation). Kyphoscoliosis, neuromuscular disorders, marked obesity, sleep apnea (Chap. 137).

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Citation

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TY - ELEC T1 - COR PULMONALE ID - 623324 Y1 - 2017 PB - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623324/all/COR_PULMONALE ER -