AUSCULTATION
HEART SOUNDS
FIGURE 112-2
S1
Loud: MS, short PR interval, hyperkinetic heart, thin chest wall. Soft: Long PR interval, heart failure, mitral regurgitation, thick chest wall, pulmonary emphysema.
S2
Normally A2 precedes P2 and splitting increases with inspiration; abnormalities include:
- Widened splitting: Right bundle branch block, PS, mitral regurgitation
- Fixed splitting (no respiratory change in splitting): Atrial septal defect
- Narrow splitting: Pulmonary hypertension
- Paradoxical splitting (splitting narrows with inspiration): Left bundle branch block, heart failure, AS
- Loud A2: Systemic hypertension
- Soft A2: Aortic stenosis
- Loud P2: Pulmonary arterial hypertension
- Soft P2: Pulmonic stenosis
S3
Low-pitched, heard best with bell of stethoscope at apex, following S2; normal in children; after age 30–35, indicates LV failure or volume overload.
S4
Low-pitched, heard best with bell at apex, preceding S1; reflects atrial contraction into a noncompliant ventricle; found in AS, hypertension, hypertrophic cardiomyopathy, and coronary artery disease (CAD).
Opening Snap (OS)
High-pitched; follows S2 (by 0.06–0.12 s), heard at lower left sternal border and apex in MS; the more severe the MS, the shorter the S2–OS interval.
Ejection Clicks
High-pitched sounds following S1 typically loudest at left sternal border; observed in dilation of aortic root or pulmonary artery, congenital AS or PS; when due to the latter, click decreases with inspiration.
Midsystolic Clicks
At lower left sternal border and apex, often followed by late systolic murmur in mitral valve prolapse.
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Citation
Kasper, Dennis L., et al., editors. "AUSCULTATION." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623300/all/AUSCULTATION.
AUSCULTATION. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623300/all/AUSCULTATION. Accessed December 9, 2024.
AUSCULTATION. (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623300/all/AUSCULTATION
AUSCULTATION [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2024 December 09]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623300/all/AUSCULTATION.
* Article titles in AMA citation format should be in sentence-case
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T1 - AUSCULTATION
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ED - Loscalzo,Joseph,
ED - Kasper,Dennis L,
ED - Fauci,Anthony S,
ED - Hauser,Stephen L,
ED - Longo,Dan L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623300/all/AUSCULTATION
PB - McGraw Hill Inc.
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DB - Harrison's Manual of Medicine
DP - Unbound Medicine
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