LEISHMANIASIS
MICROBIOLOGY
Leishmania species are extracellular, flagellated promastigotes while dwelling in their sandfly vector, but are obligate intracellular, nonflagellated amastigotes while living in vertebrate hosts, including humans.
- Organisms of the L. donovani complex usually cause visceral leishmaniasis and are present in Asia, the Middle East, the horn of Africa, the Mediterranean, and Central and South America.
- L. tropica, L. major, and L. aethiopica cause Old World cutaneous leishmaniasis and are present in Asia and in northern and sub-Saharan Africa.
- The L. mexicana complex causes New World cutaneous leishmaniasis and is present in Central America and northern South America.
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Citation
Kasper, Dennis L., et al., editors. "LEISHMANIASIS." Harrison's Manual of Medicine Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. Harrison's Manual of Medicine, harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623292/all/LEISHMANIASIS.
LEISHMANIASIS. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623292/all/LEISHMANIASIS. Accessed October 5, 2026.
LEISHMANIASIS. (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623292/all/LEISHMANIASIS
LEISHMANIASIS [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2026 October 05]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623292/all/LEISHMANIASIS.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - LEISHMANIASIS
ID - 623292
ED - Jameson,J Larry,
ED - Loscalzo,Joseph,
ED - Kasper,Dennis L,
ED - Fauci,Anthony S,
ED - Hauser,Stephen L,
ED - Longo,Dan L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623292/all/LEISHMANIASIS
PB - McGraw Hill Inc.
ET - 20
DB - Harrison's Manual of Medicine
DP - Unbound Medicine
ER -

Harrison's Manual of Medicine

