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CRYPTOCOCCOSIS

CRYPTOCOCCOSIS is a topic covered in the Harrison's Manual of Medicine.

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Microbiology and Epidemiology

Cryptococcus is a yeast-like fungus. C. neoformans and C. gattii are pathogenic for humans and can cause cryptococcosis; most clinical laboratories do not routinely distinguish between these species.

  • Worldwide, there are ~1 million cases of cryptococcosis, with >600,000 deaths annually. Most cases are in pts with AIDS.
  • Cryptococcosis due to C. neoformans is rare in the absence of impaired immunity; in contrast, C. gattiirelated disease often occurs in immunocompetent pts.
  • C. neoformans is found in soil contaminated with pigeon droppings, whereas C. gattii is associated with eucalyptus trees. Most cases are acquired via inhalation, which results in pulmonary infection.

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Citation

Loscalzo, Joseph, et al., editors. "CRYPTOCOCCOSIS." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623285/all/CRYPTOCOCCOSIS.
CRYPTOCOCCOSIS. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623285/all/CRYPTOCOCCOSIS. Accessed April 21, 2019.
CRYPTOCOCCOSIS. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623285/all/CRYPTOCOCCOSIS
CRYPTOCOCCOSIS [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 21]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623285/all/CRYPTOCOCCOSIS.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - CRYPTOCOCCOSIS ID - 623285 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623285/all/CRYPTOCOCCOSIS PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -