TALAROMYCOSIS (PENICILLIOSIS)
Talaromyces marneffei (formerly Penicillium marneffei) is a leading cause of opportunistic infection in pts with immunocompromise (e.g., due to AIDS) in Southeast Asia and is acquired by spore inhalation. Clinical manifestations are similar to those of disseminated histoplasmosis, with fever, fatigue, weight loss, lymphadenopathy, hepatomegaly, and skin lesions resembling molluscum contagiosum. The organism grows readily in culture and produces a distinctive red pigment. AmB is the initial treatment of choice for severely ill pts; less severe disease may be treated with itraconazole (200 mg bid for 12 weeks). Suppressive therapy with itraconazole (200 mg/d) may be indicated for pts with HIV infection or AIDS until the CD4+ T cell count is >100 cells/μL for ≥6 months.
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Citation
Kasper, Dennis L., et al., editors. "TALAROMYCOSIS (PENICILLIOSIS)." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623278/all/TALAROMYCOSIS__PENICILLIOSIS_.
TALAROMYCOSIS (PENICILLIOSIS). In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623278/all/TALAROMYCOSIS__PENICILLIOSIS_. Accessed November 10, 2024.
TALAROMYCOSIS (PENICILLIOSIS). (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623278/all/TALAROMYCOSIS__PENICILLIOSIS_
TALAROMYCOSIS (PENICILLIOSIS) [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2024 November 10]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623278/all/TALAROMYCOSIS__PENICILLIOSIS_.
* Article titles in AMA citation format should be in sentence-case
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ED - Loscalzo,Joseph,
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ED - Fauci,Anthony S,
ED - Hauser,Stephen L,
ED - Longo,Dan L,
BT - Harrison's Manual of Medicine
UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623278/all/TALAROMYCOSIS__PENICILLIOSIS_
PB - McGraw Hill Inc.
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DB - Harrison's Manual of Medicine
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