PARACOCCIDIOIDOMYCOSIS
To view the entire topic, please log in or purchase a subscription.
Harrison’s Manual of Medicine 20th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:
-- The first section of this topic is shown below --
Paracoccidioidomycosis (South American blastomycosis) is caused by Paracoccidioides brasiliensis, a dimorphic fungus acquired by inhalation from environmental sources. Acute infection occurs in young or immunocompromised pts and manifests as disseminated infection of the reticuloendothelial system. Chronic infection accounts for 90% of cases and presents primarily as progressive pulmonary disease with occasional ulcerative and nodular mucocutaneous lesions in the nose and mouth. Diagnosis relies on culture of the organism. Itraconazole (100–200 mg/d for 6–12 months) is effective, but AmB may be required for seriously ill pts.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
Paracoccidioidomycosis (South American blastomycosis) is caused by Paracoccidioides brasiliensis, a dimorphic fungus acquired by inhalation from environmental sources. Acute infection occurs in young or immunocompromised pts and manifests as disseminated infection of the reticuloendothelial system. Chronic infection accounts for 90% of cases and presents primarily as progressive pulmonary disease with occasional ulcerative and nodular mucocutaneous lesions in the nose and mouth. Diagnosis relies on culture of the organism. Itraconazole (100–200 mg/d for 6–12 months) is effective, but AmB may be required for seriously ill pts.
There's more to see -- the rest of this topic is available only to subscribers.