PARACOCCIDIOIDOMYCOSIS is a topic covered in the Harrison's Manual of Medicine.

To view the entire topic, please or purchase a subscription.

Harrison’s Manual of Medicine 19th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:

Harrison’s Manual of Medicine - App + Web

-- The first section of this topic is shown below --

Paracoccidioidomycosis (South American blastomycosis) is caused by Paracoccidioides brasiliensis, a dimorphic fungus acquired by inhalation from environmental sources. Acute infection occurs in young or immunocompromised pts and manifests as disseminated infection of the reticuloendothelial system. Chronic infection accounts for 90% of cases and presents primarily as progressive pulmonary disease with occasional ulcerative and nodular mucocutaneous lesions in the nose and mouth. Diagnosis relies on culture of the organism. Itraconazole (100–200 mg/d for 6–12 months) is effective, but AmB may be required for seriously ill pts.

-- To view the remaining sections of this topic, please or purchase a subscription --