PARACOCCIDIOIDOMYCOSIS

PARACOCCIDIOIDOMYCOSIS is a topic covered in the Harrison's Manual of Medicine.

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Paracoccidioidomycosis (South American blastomycosis) is caused by Paracoccidioides brasiliensis, a dimorphic fungus acquired by inhalation from environmental sources. Acute infection occurs in young or immunocompromised pts and manifests as disseminated infection of the reticuloendothelial system. Chronic infection accounts for 90% of cases and presents primarily as progressive pulmonary disease with occasional ulcerative and nodular mucocutaneous lesions in the nose and mouth. Diagnosis relies on culture of the organism. Itraconazole (100–200 mg/d for 6–12 months) is effective, but AmB may be required for seriously ill pts.

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Citation

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TY - ELEC T1 - PARACOCCIDIOIDOMYCOSIS ID - 623277 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623277/all/PARACOCCIDIOIDOMYCOSIS PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -