NOCARDIOSIS

NOCARDIOSIS is a topic covered in the Harrison's Manual of Medicine.

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MICROBIOLOGY

Nocardiae are branching, beaded, gram-positive filaments that usually give positive results with modified acid-fast stains. These saprophytic aerobic actinomycetes are common in soil.

  • Nine species or species complexes are most commonly associated with human disease.
  • Speciation of nocardiae is precluded in most clinical laboratories, although improvements in mass spectrometry–based techniques may change this limitation in high-resource countries.
  • Nocardia brasiliensis is most often associated with localized skin lesions.

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MICROBIOLOGY

Nocardiae are branching, beaded, gram-positive filaments that usually give positive results with modified acid-fast stains. These saprophytic aerobic actinomycetes are common in soil.

  • Nine species or species complexes are most commonly associated with human disease.
  • Speciation of nocardiae is precluded in most clinical laboratories, although improvements in mass spectrometry–based techniques may change this limitation in high-resource countries.
  • Nocardia brasiliensis is most often associated with localized skin lesions.

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