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Aphasia

Aphasia is a topic covered in the Harrison's Manual of Medicine.

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Aphasias are disturbances in the comprehension or production of spoken or written language. Clinical examination should assess spontaneous speech (fluency), comprehension, repetition, naming, reading, and writing. A classification scheme is presented in Table 55-1. In nearly all right-handed individuals and many left-handed pts, language localization is in the left hemisphere.

TABLE 55-1: CLINICAL FEATURES OF APHASIAS AND RELATED CONDITIONS COMMONLY SEEN IN CEREBROVASCULAR ACCIDENTS
ComprehensionRepetition of Spoken LanguageNamingFluency
Wernicke’sImpairedImpairedImpairedPreserved or increased
Broca’sPreserved (except grammar)ImpairedImpairedDecreased
GlobalImpairedImpairedImpairedDecreased
ConductionPreservedImpairedImpairedPreserved
Nonfluent (anterior) transcorticalPreservedPreservedImpairedImpaired
Fluent (posterior) transcorticalImpairedPreservedImpairedPreserved
IsolationImpairedEcholaliaImpairedNo purposeful speech
AnomicPreservedPreservedImpairedPreserved except for word-finding pauses
Pure word deafnessImpaired only for spoken languageImpairedPreservedPreserved
Pure alexiaImpaired only for readingPreservedPreservedPreserved

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Citation

Loscalzo, Joseph, et al., editors. "Aphasia." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623194/all/Aphasia.
Aphasia. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623194/all/Aphasia. Accessed April 18, 2019.
Aphasia. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623194/all/Aphasia
Aphasia [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 18]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623194/all/Aphasia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Aphasia ID - 623194 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623194/all/Aphasia PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -