Chapter 207: Cardiovascular Disease Prevention
Atherosclerotic cardiovascular disease is the leading cause of death worldwide; prevention is targeted at modifiable risk factors (Table 207-1). Identification and control of these attributes reduce cardiovascular event rates.
Modifiable Risk Factors  Cigarette smoking  Dyslipidemias (↑LDL or ↓HDL)  Hypertension  Diabetes mellitus  Obesity  Sedentary lifestyle  | 
Unmodifiable Risk Factors  Premature coronary heart disease in first-degree relatives (age <55 in men, <65 in women)  Age (men ≥45 years; women ≥55 years)  Male sex  | 
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Citation
Kasper, Dennis L., et al., editors. "Chapter 207: Cardiovascular Disease Prevention." Harrison's Manual of Medicine, 20th ed., McGraw Hill Inc., 2020. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623130/all/Chapter_207:_Cardiovascular_Disease_Prevention. 
Chapter 207: Cardiovascular Disease Prevention. In: Kasper DLD, Fauci ASA, Hauser SLS, et al, eds. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623130/all/Chapter_207:_Cardiovascular_Disease_Prevention. Accessed November 4, 2025.
Chapter 207: Cardiovascular Disease Prevention. (2020). In Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (Eds.), Harrison's Manual of Medicine (20th ed.). McGraw Hill Inc.. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623130/all/Chapter_207:_Cardiovascular_Disease_Prevention
Chapter 207: Cardiovascular Disease Prevention [Internet]. In: Kasper DLD, Fauci ASA, Hauser SLS, Longo DLD, Jameson JLJ, Loscalzo JJ, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2020. [cited 2025 November 04]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623130/all/Chapter_207:_Cardiovascular_Disease_Prevention.
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Harrison's Manual of Medicine

