Type your tag names separated by a space and hit enter

Chronic Kidney Disease and Uremia

Chronic Kidney Disease and Uremia is a topic covered in the Harrison's Manual of Medicine.

To view the entire topic, please or purchase a subscription.

Harrison’s Manual of Medicine 19th edition provides 600+ internal medicine topics in a rapid-access format. Download Harrison’s App to iPhone, iPad, and Android smartphone and tablet. Explore these free sample topics:

Harrison’s Manual of Medicine - App + Web

-- The first section of this topic is shown below --


The prevalence of chronic kidney disease (CKD), generally defined as a long-standing, irreversible impairment of kidney function, is substantially greater than the number of pts with end-stage renal disease (ESRD), now ≥500,000 in the United States. There is a spectrum of disease related to decrements in renal function; clinical and therapeutic issues differ greatly depending on whether the glomerular filtration rate (GFR) reduction is moderate (stage 3 CKD, 30–59 mL/min per 1.73 m2) (see Table 46-1), severe (stage 4 CKD, 15–29 mL/min per 1.73 m2), or “end-stage renal disease” (stage 5 CKD, <15 mL/min per 1.73 m2). Dialysis is usually required once GFR <10 mL/min per 1.73 m2. Common causes of CKD are outlined in Table 139-1.

Diabetic nephropathy
Hypertensive nephropathya
Renovascular disease (ischemic nephropathy)
Polycystic kidney disease
Reflux nephropathy and other congenital renal diseases
Interstitial nephritis, including analgesic nephropathy
HIV-associated nephropathy
Transplant allograft failure (“chronic rejection”)
aOften diagnosis of exclusion; very few pts undergo renal biopsy; may be occult renal disease with hypertension.

-- To view the remaining sections of this topic, please or purchase a subscription --


* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Chronic Kidney Disease and Uremia ID - 623056 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623056/all/Chronic_Kidney_Disease_and_Uremia PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -