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Pulmonary Hypertension

Pulmonary Hypertension is a topic covered in the Harrison's Manual of Medicine.

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Definition

Elevation of pulmonary artery (PA) pressure due to pulmonary vascular or parenchymal disease, increased left heart filling pressures, or a combination. Table 127-1 lists etiologies by categories.

TABLE 127-1: CLASSIFICATION OF PULMONARY HYPERTENSION
  1. Pulmonary Arterial Hypertension
    • Idiopathic
    • Heritable (mutations/familial cases)
    • Collagen vascular diseases (e.g., scleroderma, SLE, RA)
    • Congenital systemic to pulmonary shunts (e.g., ventricular septal defect, patent ductus arteriosus, atrial septal defect)
    • Portal hypertension
    • HIV infection
    • Drugs or toxins (e.g., fenfluramine)
  2. Pulmonary Hypertension Due to Left Heart Disease
    • LV systolic or diastolic dysfunction
    • Left-sided valvular disease
  3. Pulmonary Hypertension Due to Lung Disease or Hypoxia
    • Chronic obstructive lung disease
    • Interstitial lung disease
    • Sleep-disordered breathing
    • Chronic hypoventilation
  4. Chronic Pulmonary Thromboembolic Disease
    • Chronic pulmonary embolism
  5. Miscellaneous
    • Systemic conditions (e.g., sarcoidosis, pulmonary histiocytosis)
    • Hematologic conditions (e.g., myeloproliferative diseases)
Abbreviations: RA, rheumatoid arthritis.

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Citation

Loscalzo, Joseph, et al., editors. "Pulmonary Hypertension." Harrison's Manual of Medicine, 19th ed., McGraw Hill Inc., 2017. harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623042/all/Pulmonary_Hypertension.
Pulmonary Hypertension. In: Loscalzo J, Jameson JL, Longo DL, et al, eds. Harrison's Manual of Medicine. 19th ed. McGraw Hill Inc.; 2017. https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623042/all/Pulmonary_Hypertension. Accessed April 18, 2019.
Pulmonary Hypertension. (2017). In Loscalzo, J., Jameson, J. L., Longo, D. L., Hauser, S. L., Fauci, A. S., & Kasper, D. L. (Eds.), Harrison's Manual of Medicine. Available from https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623042/all/Pulmonary_Hypertension
Pulmonary Hypertension [Internet]. In: Loscalzo J, Jameson JL, Longo DL, Hauser SL, Fauci AS, Kasper DL, editors. Harrison's Manual of Medicine. McGraw Hill Inc.; 2017. [cited 2019 April 18]. Available from: https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623042/all/Pulmonary_Hypertension.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Pulmonary Hypertension ID - 623042 ED - Loscalzo,Joseph, ED - Jameson,J Larry, ED - Longo,Dan L, ED - Hauser,Stephen L, ED - Fauci,Anthony S, ED - Kasper,Dennis L, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623042/all/Pulmonary_Hypertension PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -