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CHRONIC MYELOID LEUKEMIA (CML)

CHRONIC MYELOID LEUKEMIA (CML) is a topic covered in the Harrison's Manual of Medicine.

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CML is a clonal malignancy usually characterized by splenomegaly and production of increased numbers of granulocytes; course is initially indolent but eventuates in leukemic phase (blast crisis) that has a poorer prognosis than de novo AML; rate of progression to blast crisis is variable; overall survival averages 4 years from diagnosis.

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Citation

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TY - ELEC T1 - CHRONIC MYELOID LEUKEMIA (CML) ID - 623593 ED - Fauci,Anthony S, ED - Hauser,Stephen L, ED - Jameson,J Larry, ED - Kasper,Dennis L, ED - Longo,Dan L, ED - Loscalzo,Joseph, BT - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623593/all/CHRONIC_MYELOID_LEUKEMIA__CML_ PB - McGraw Hill Inc. ET - 19 DB - Harrison's Manual of Medicine DP - Unbound Medicine ER -