Shock is a topic covered in the Harrison's Manual of Medicine.

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DEFINITION

Condition of severe impairment of tissue perfusion leading to cellular injury and dysfunction. Rapid recognition and treatment are essential to prevent irreversible organ damage and death. Common causes are listed in Table 11-1.

TABLE 11-1: CATEGORIES OF SHOCK

Hypovolemic shock

  •  Hemorrhage
  •  Intravascular volume depletion (e.g., vomiting, diarrhea, ketoacidosis)
  •  Internal sequestration (ascites, pancreatitis, intestinal obstruction)

Cardiogenic shock

  •  Myopathic (acute MI, fulminant myocarditis)
  •  Mechanical (e.g., acute mitral regurgitation, ventricular septal defect, severe aortic stenosis, aortic dissection with aortic insufficiency)
  •  Arrhythmic

Extracardiac obstructive shock

  •  Pericardial tamponade
  •  Massive pulmonary embolism
  •  Tension pneumothorax

Distributive shock (profound decrease in systemic vascular tone)

  •  Sepsis
  •  Toxic overdoses
  •  Anaphylaxis
  •  Neurogenic (e.g., spinal cord injury)
  •  Endocrinologic (Addison’s disease, myxedema)

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Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Shock ID - 623024 Y1 - 2017 PB - Harrison's Manual of Medicine UR - https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623024/all/Shock ER -