Harrison's Manual of Medicine 17/e
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Acid-Base Disorders

Respiratory Alkalosis

Excessive ventilation causes a primary reduction in CO2 and ↑ pH in pneumonia, pulmonary edema, interstitial lung disease, and asthma. Pain and psychogenic causes are common; other etiologies include fever, hypoxemia, sepsis, delirium tremens, salicylates, hepatic failure, mechanical overventilation, and CNS lesions. Pregnancy is associated with a mild respiratory alkalosis. Severe respiratory alkalosis may acutely cause seizures, tetany, cardiac arrhythmias, or loss of consciousness.

TREATMENT
Treatment should be directed at the underlying disorders. In psychogenic cases, sedation or a rebreathing bag may be required.

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